Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. R&D is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies that matter most. Today, we are at a unique moment in biomedical innovation.

Process Technician

Our breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members, who understand the importance and impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need, when they need them.

 

What You Will Achieve

You will support the execution of production according to Standard Operating Procedures and production schedule. Working with interdisciplinary teams, you will implement process improvements and participate in process troubleshooting.

As part of technical operations, you will be developing and applying your knowledge of procedures, techniques, tools, materials and equipment. Your receptiveness to new ideas will enhance the team’s ability to achieve goals and targets.  You will follow standard procedures to complete tasks and identify process issues or problems that involve direct application of your skills/knowledge.

It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

 

How You Will Achieve It

• Manage own time, professional development and be accountable for own results.
• Support implementation of new technology for process execution and/or analysis.
• Review documentation daily as well as perform data entry.
• Assist in inventory tracking, maintenance scheduling, and troubleshooting of mechanical equipment.
• Executes Standard Operating Procedures (SOPs) for unit operations and maintain current training status for SOPs.
• Complete a variety of accountability reports, pull samples for identification/testing and perform routine product/process functional tests online.
• Responsible for daily facility sanitization of the manufacturing suites controlled environments in accordance with routine requirements and special sanitization requests as needed.

 

Qualifications

Must-Have

• High School Diploma or GED

 

Nice-to-Have

• Basic mechanical knowledge and experience in using hand tools
• Manufacturing experience in a Good Manufacturing Practices (cGMP) or other regulated environment

 

PHYSICAL/MENTAL REQUIREMENTS

• Requires the moving of heavy equipment and the ability to lift ~50 pounds. The incumbent needs to take the necessary safety precautions when working with pressurized systems, steam, and corrosive chemicals.

• The incumbent is required to attain detail knowledge of the operational equipment.

• The incumbent will be required to solve problems regarding site assessment, specific units used in Biopharmaceutical manufacturing.

• The incumbent must be able to express ideas into SOPs, MFRs and be able to use a multitude of programs including Excel, Word, Power Point, etc.

 

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

 

• 12 hour; Rotating Shift
• Must be able to work in a GMP environment for long periods of time.

 

ADDITIONAL INFORMATION:

• Work Location Assignment: On Premise
• Last Day to Apply: January 16, 2025
• This position does not provide relocation assistance.

 

 

The salary for this position ranges from $23.28 to $38.80 per hour. In addition, this position offers eligibility for overtime, weekend, holiday and other pay premiums depending on the work schedule and the Company’s policies. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided applies only to the United States – Massachusetts – Andover location.

Associate Research Fellow Drug Product Design

The purpose of this position is to act as a resident pharmaceutical science subject matter expert in spray dried dispersion (SDD) technology.  This role will collaborate with formulation scientists to influence small molecule drug candidate selection with respect to application of SDD technology to improve drug delivery and bio-performance. This role will be responsible for development and optimal SDD composition selection as well as characterization to ensure appropriate in vivo performance.  As an individual and as part of a network, this role will contribute to the formation of predictive models, efficiency in process and workflows, as well as exploration of more efficient and/or greener amorphous solid dispersion (ASD) manufacturing technologies.  This position will perform technology transfer activities with our GMP SDD vendor network.

 

ROLE RESPONSIBILITIES

• Evaluate the physicochemical properties of potential small molecule drug candidates to inform an ASD formulation strategy and developability risk assessment.
• Design and develop fit for purpose and diagnostic SDD formulations for preclinical studies.
• Be a subject matter expert in formulation and process development for SDDs supporting multiple discovery teams across several research units.
• Apply first-principles understanding of thermodynamics and kinetic processes to dissolution and precipitation of drugs in biorelevant conditions as well as physical and chemical stability in the solid state.
• Develop strategic collaborations with academic and industrial researchers for addressing gaps in fundamental or applied science related to amorphous solid dispersions.
• Conduct novel research and present significant findings via internal and external presentations or publications.
• Supervision of laboratory staff to support SDD production and assessment.
• Work collaboratively with scientists across the organization to understand and address key challenges in the ASD space.

 

BASIC QUALIFICATIONS

• PhD  with 12+ years experience in industrial spray dried dispersion technology or related disciplines
• Experience in formulation and manufacturing of SDDs targeted at bioavailability enhancement
• Experience working independently and collaboratively in a laboratory environment

 

PREFERRED QUALIFICATIONS

• Experience in breaking down and isolating the controlling physics of complex processes for experimental design
• Experience in designing and conducting hypothesis driven laboratory experiments
• Generating, interpreting, and integrating experimental data into mathematical models to progress the understanding of complex materials and processes
• Experience in pharmacokinetic modeling and simulations using Gastroplus, Simcyp, or Phoenix
• Strong organizational skills, interpersonal skills, teamwork skills, strong written and verbal communication skills
• Ability to prioritize and manage multiple projects and activities while managing tight timelines
• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

 

PHYSICAL/MENTAL REQUIREMENTS

• Includes activities in both laboratory and office settings. Candidate must be able to perform routine laboratory tests and procedures. Ability to perform mathematical calculations and ability to perform complex data analysis.

 

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

 

• Occasional travel for conferences/training (domestic and international)

Relocation support available

Work Location Assignment: On Premise

Obesity – Global Study Manager II (Sr. Manager)

As a Senior Manager, your advanced knowledge of the principles and concepts in the obesity disease area and comprehensive knowledge of other disciplines will enable you to lead complex projects across the division. Your ability to develop and manage plans will facilitate in achieving objectives, interpreting internal and external business challenges and recommending best practices for improvements. While managing complex project environments, you will be able to anticipate and troubleshoot roadblocks and influence teams to achieve targets for the division.

 

It is your problem solving ability and patience that will make Pfizer ready to achieve new milestones and help patients across the globe.

 

How You Will Achieve It

• Develop ideas, lead/co-lead complex projects across business units and develop plans to achieve objectives.
• Approve the Study Startup, Study Monitoring and protocol recruitment plans.
• Resolve escalated issues identified by the site activation sub team in partnership with the Study Operations Manager.
• Work proactively with country offices and data management functions to ensure alignment on data flow and timely delivery.
• Manage Operational Study Management for one or more studies of limited complexity or a unique part of a larger study.
• Forecast and manage the Clinical Trial Budget for the program.
• Provide country and regional level input to country outreach surveys.
• Create awareness by working as a cross functional Team Leader to deliver site intelligence initiatives with a variety of stakeholders, both internal and external.
• Approve and oversee drug supply management, manage flow of drug supply to the sites.
• Participate in global initiatives to improve operational efficiencies.
• Evaluate study progress reports and results for overall compliance and recommends corrective action or study termination for non-performance.
• Maintain regular communications with investigator sites to gather status updates, informal and formal performance metrics, and study-level feedback.

 

Qualifications

Must-Have

• Recent experience overseeing Obesity studies
• Bachelor’s Degree
• 7+ years’ experience
• Applicable pharmaceutical industry experience
• Working knowledge of Good Clinical Practices, monitoring, clinical and regulatory operations
• Demonstrated project management / leadership experience
• Ability to evaluate, interpret and present complex issues and data to support risk
• Excellent communication skills, both written and verbal; must be fluent in English
• Effective decision maker, analytical and solution-oriented
• Proficiency in Microsoft Office Suite

 

Nice-to-Have

• Master’s degree.
• Broad based experience in clinical research

Work Location Assignment: Remote – Field Based

Medical Digital Health Lead, Sr. Director

The Medical Digital Health Lead, Sr. Director plays a pivotal role in closing care gaps through Medical digital innovation. This individual works within Global Medical Affairs with the goal to manage the governance and process navigation of the Biopharma Medical Digital Health portfolio (e.g., Software as a Medical Device) This role will work in close collaboration with therapeutic areas, Global Digital, Legal / Compliance, Commercial / CMO, R&D, and other partners.
The role demands a blend of scientific background, knowledge of SaMD landscape, and matrix leadership skills to navigate across global Pfizer functions. The responsibility of the incumbent is to navigate and govern Biopharma Digital Health initiatives working in concert with other Pfizer teams across the life cycle.

 

ROLE RESPONSIBILITIES

• Help to establish a new governance model around the development of medical digital health initiatives at Pfizer Inc and across Biopharma
• Support therapeutic areas and functions to close care gaps by overseeing medical digital health initiatives from ideation to lifecycle management.
• Lead a matrix of SMEs from different therapeutic areas and functions to develop robust processes including adoption scenarios (peak user numbers), medical risk & benefits analysis which are presented to senior leadership for discussion and funding decisions.
• Develop evidence generation plans together with clinical and medical SMEs
•   Negotiate across key domains (Legal, Compliance, Regulatory, WRDM/GPD, Digital, TA, Safety, etc.) integrating each domain’s SME perspective in the digital health solutions product lifecycle
• Spearhead scientific research efforts in the field of digital health evaluation methodologies using skills and experience from established drug R&D processes (e.g. Good Clinical Practice)
• Liaise with key opinion leaders, healthcare professionals, and patient groups to gather insights on care gaps and foster partnerships to enable successful deployment (launch) of digital health therapies
• Continuous improvement of life cycle processes and reduction of latency between decision points

 

BASIC QUALIFICATIONS

• Bachelor’s degree required and minimum of 15 years’ experience in the healthcare industry, with at least 5 years of main focus in the field of medical  digital health; Masters/MBA and 13+ years; PharmD/PHD and 10+ years; MD and 5+ years
• Demonstrated experience and results in developing and deploying medical digital health solutions (min. 2 key experiences)
• Track record in leading matrix development teams in high-stakes medical digital health projects, e.g. within academic consortia, x-functional Pfizer teams
• Previous exposure to governance / regulatory negotiations around digital health solutions
• Ability to design evidence generation plans (2 key experiences)
• Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

 

PREFERRED QUALIFICATIONS

• Business experience in the field of digital health solutions, e.g.  venture capital negotiations, involvement in start-up formation in the field of digital health solutions
• MD or PhD in a relevant biomedical field.
• Strong stakeholder network in digital health, e.g. previous or active member in US/international societies and initiatives around digital health solutions
• Clinical experience in treating patients with digital health solutions
• Track record of being thought leader in the field of digital health solutions, e.g. scientific publications or public speeches on the topic.

 

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Up to 30% of travel required